GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Archived. This submission is more than a year old. Votes and new comments are closed, and some of the advice in it may have been superseded — check the community wiki for the current version.
8.8k
c/reconstitution·posted 2 years ago by u/janek_ferrari

what changed for me between week 85 and week 39

PSA Cold Box ×4 Slow Clap ×3 Clean Column ×3

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking units against ApoB for 3 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

10,573 up / 1,801 down85% upvoted52 commentsid erlmkg16 May 2024

52 comments

15 in this archive, depth 4

best — the order this archive was captured in

u/viktor_erdogan1.3k points·2 years ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

replysharereportpermalink
u/india_generic_g834 points·2 years ago

Did you write the concentration on the vial?

replysharereportpermalink
u/oskar_ibarra404 points·2 years ago

Cosigning. The concentration on the vial in marker is load-bearing.

replysharereportpermalink
u/quiet_reader_99741 points·2 years ago

15mg vial, 2mL water, concentration is 15/2 — write it on the vial afterwards

replysharereportpermalink
u/lurker_for_years265 points·2 years ago

Slight fix: the number was 98.1, not 98.0. Decimal point, but a fairly consequential one.

replysharereportpermalink
u/runa_grimaldi568 points·2 years ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

replysharereportpermalink
[deleted]373 points·2 years ago

[deleted]

replysharereportpermalink
u/vial_math_verasyringe math200 points·2 years ago

Did you write the concentration on the vial?

replysharereportpermalink
u/yusuf_nakamura-11 points·2 years ago

The confident tone is doing a lot of work that the evidence is not.

replysharereportpermalink
u/sock_puppet_spotter521 points·2 years ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

replysharereportpermalink
u/bac_water_banditMOD344 points·2 years ago

Tracking number removed. It identifies both ends of a shipment.

replysharereportpermalink
u/emil_zamora507 points·2 years ago

20mg vial, 2mL water, concentration is 20/2 — write it on the vial afterwards

replysharereportpermalink
u/adaeze_cabrera254 points·2 years ago

Cosigning. The concentration on the vial in marker is load-bearing.

replysharereportpermalink
u/lurker_for_years189 points·2 years ago

Respectfully this is a sample of one presented as a finding.

replysharereportpermalink
u/rina_bergstrom63 points·2 years ago·edited

dead space is real and the syringe matters

replysharereportpermalink
Permalinked branches
Deep branches get their own page so a single reply chain can be linked and read on its own.
About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

88kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
c/reconstitution rules
  1. Show your numbers. "How many units?" with no mg and no mL cannot be answered.
  2. Never post a calculation as advice without stating the concentration it assumes.
  3. No sterile-compounding-for-others discussion. Personal handling only.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.