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9.2k

the Netherlands: mg/mL, and what it actually costs here

Explainer Sourced ×8 Slow Clap ×1 The Quiet One ×1

Confession thread, sort of.

I went from 5mg to 1.7mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 2 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have reflux I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 95 reads it before doing the same thing.

9,698 up / 473 down95% upvoted36 commentsid 14dww721 Mar 2025

36 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/bac_water_banditMOD1k points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/saskia_mwangi416 points·1 year ago

more water means more units for the same dose, which means finer resolution

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u/karim_ilunga246 points·1 year ago

never post a calculation as advice without stating the concentration

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u/quiet_reader_99155 points·1 year ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/ledger_modmod · vetting715 points·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/anya_antonsen600 points·1 year ago

u-100 syringe, not u-40, or your math is off by factor of 8

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u/nabila_espinoza393 points·1 year ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/india_generic_g374 points·1 year ago

Show the arithmetic. Where did the units come from?

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[removed]256 points·1 year ago

[removed by moderator]

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u/quiet_reader_99OP187 points·1 year ago

stopper coring on the 16th draw because you keep using the same entry point. rotate.

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u/liv_nkemelu91 points·1 year ago

show your working or it is unhelpful

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u/freya_onwuka241 points·1 year ago·edited

You have restated the marketing copy. What is the actual substance here.

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u/quiet_reader_99OP87 points·1 year ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/tomas_kimani308 points·1 year ago

dead space is real and the syringe matters

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u/ahmed_rasmussen169 points·1 year ago

Show the arithmetic. Where did the units come from?

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u/oskar_ibarra263 points·1 year ago

the concentration on the vial in marker is the most important step

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u/quiet_reader_99OP101 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/viktor_erdogan165 points·1 year ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/niels_roos196 points·1 year ago

dead space is real and the syringe matters

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u/andres_sorensen97 points·1 year ago

never post a calculation as advice without stating the concentration

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u/aurel_boateng54 points·1 year ago

more water means more units for the same dose, which means finer resolution

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u/britta_nakamura12 points·1 year ago

more water means more units for the same dose, which means finer resolution

Adding to this: reconstitution is doing more work than the comment implies.

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u/georgi_adebayo64 points·1 year ago

Cored the stopper on my 2th draw because I kept using the same entry point. Rotate the puncture site.

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u/rina_bergstrom116 points·1 year ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/oskar_ibarra142 points·1 year ago

Is that 10mg vial or 21mg?

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u/ilias_cabrera-25 points·1 year ago

Show the arithmetic. Where did the units come from?

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u/anya_antonsen1 point·1 year ago

This is correct. 1mL versus 23mL is the common mistake.

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u/sofia_danquah1 point·1 year ago

Slight fix: the number was 98.4, not 98.3. Decimal point, but a fairly consequential one.

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u/runa_grimaldi76 points·1 year ago

Spent 13 weeks confused about concentration math until someone showed me the table. 10mg, 1mL, concentration is 10/1.

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u/ines_lindqvist41 points·1 year ago

swirl, do not shake, or you are courting oxidation

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The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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