small win: units stopped being a problem at week 11
Been lurking in c/semaglutide for about 12 months and finally have something worth posting.
Short version: week 44, 0.5mg, and dead space is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 9 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 38.
best — the order this archive was captured in
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
Disagree but this is the good kind of wrong — it is specific enough to be checked.
bacteriostatic and sterile water are not interchangeable, do not use them that way
dead space is real and the syringe matters
Yeah, showing the arithmetic is the fastest way for someone to spot the error.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
I am going to push back on this slightly.
u-100 syringe, not u-40, or your math is off by factor of 17
Mechanistically the bit that matters is concentration. It explains most of the early profile and a decent chunk of the outcome.
i am begging people to write down the concentration
Not to be pedantic but dead space and insulin syringe are being used interchangeably and they are not interchangeable in real life.
Mechanistically the bit that matters is concentration.
Adding to this: dead space is doing more work than the comment implies.
This is correct. 3mL versus 17mL is the common mistake.
swirl, do not shake, or you are courting oxidation
dosing errors come from people reconstituting two vials differently and forgetting which is which
dosing errors come from people reconstituting two vials differently and forgetting which is which
Yes, exactly this, and it is the bit that took me 11 weeks to accept.
dosing errors come from people reconstituting two vials differently and forgetting which is which Yes, exactly this, and it is the bit that took me 11
Disagree on that part. 96.8% and 96.2% on the same vial is normal.
Tracking number removed. It identifies both ends of a shipment.
more water means more units for the same dose, which means finer resolution
the concentration on the vial in marker is the most important step
- 1The practical rule people converge on is 28 days at fridge temperature after…6 comments in this branch · started by u/runa_grimaldi
- 2Mechanistically the bit that matters is concentration. It explains most of…6 comments in this branch · started by u/erez_perrin