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c/orforglipron·posted 8 months ago by u/freya_marchand

what would you tell week-1 you about ATTAIN

Discussion Long Haul ×7

Week 2 update. 13kg down from the start, muscle cramps basically gone since about week 54.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

563 up / 116 down83% upvoted10 commentsid y828u79 Nov 2025

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5 in this archive, depth 3sorted by:

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u/salma_almeida101 points·8 months ago

the fatigue profile is speculative at this stage

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u/ayesha_erdogan-34 points·8 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/yannick_salinas68 points·8 months ago·edited

small molecule purity is different testing than peptides

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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