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c/orforglipron·posted 3 months ago by u/first_hundred

my triglycerides moved and I cannot work out whether small molecule is why

Speculation Cold Box ×4

Been lurking in c/hplc for about 16 months and finally have something worth posting.

Short version: week 8, 2.4mg, and oral GLP-1 is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 23 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 14.

3,242 up / 2,380 down58% upvoted21 commentsid xe0a9b1 Apr 2026

21 comments

5 in this archive, depth 4

best — the order this archive was captured in

u/dario_boateng71 points·3 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/anders_karlsen61 points·3 months ago
IANAD and neither is anyone upvoting this
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u/incretin_ivypharmacology89 points·3 months ago

Has anyone actually got this in writing, or is it forum lore at this point?

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u/batch_number_bertievetting42 points·3 months ago

the supply conversation changes if this approves

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u/muscle_cramp_mo30 points·3 months ago

Which country? Half the answers in this thread only apply in Canada.

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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