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c/orforglipron·submitted 3 months ago by u/tidy_vialdrawer_watch28

what would you tell week-1 you about non-peptide

Trial Databranch of 7 comments

Trying to settle this properly because the thread from last year went in circles. The claim: small molecule matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 16 months without either producing anything. What would actually settle it is 9 people measuring the…

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7 comments, started 3 months ago
u/brigade_detector32 points·3 months ago

ATTAIN and ACHIEVE are phase 21 trials

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u/tidy_vialdrawer_watch28OP21 points·3 months ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/aksel_kjaer6 points·3 months ago

phase 5 data is interesting, phase 16 will tell the real story

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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