unpopular opinion: orforglipron is massively overrated
Posting this because I searched for it and got nothing useful. Setup: 12.5mg, week 82, sulphur burps present but not ruining anything. I changed exactly one variable — non-peptide — and tracked it for 23 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it.…
Strongly agree. The supply impact would be huge.
This is the "correlation is mechanism" thing again. You changed three variables at once.
small molecule purity is different testing than peptides
Yeah, small molecule changes the whole game.
Disagree but this is the good kind of wrong — it is specific enough to be checked.
Not convinced. The evidence does not support that reading.
That is net peptide content, not purity. Different number, different meaning.
small molecule purity is different testing than peptides