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Single comment threadYou are looking at one branch of unpopular opinion: orforglipron is massively overrated — 47 comments in the full submission. View in context.
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c/orforglipron·submitted 1 year ago by u/sofia_petrescu

unpopular opinion: orforglipron is massively overrated

Speculationbranch of 6 comments

Posting this because I searched for it and got nothing useful. Setup: 12.5mg, week 82, sulphur burps present but not ruining anything. I changed exactly one variable — non-peptide — and tracked it for 23 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it.…

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6 comments, started 1 year ago
u/trialwatch_theotrial nerd211 points·1 year ago
search before post, but also, welcome
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u/whois_wanda70 points·1 year ago

This is correct. ATTAIN data is phase 11.

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u/trialwatch_theotrial nerd27 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/erez_yilmaz22 points·1 year ago

no cold chain means non-peptide, if approved

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[deleted]15 points·1 year ago

[deleted]

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u/lucia_bruun7 points·1 year ago

the small molecule is whether this actually works long-term

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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