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Single comment threadYou are looking at one branch of my eGFR moved and I cannot work out whether lyophilised is why — 51 comments in the full submission. View in context.
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c/coldchain·submitted 2 years ago by u/low_appetite_lisa

my eGFR moved and I cannot work out whether lyophilised is why

Databranch of 7 comments

Genuinely asking, not being difficult. Everyone in c/glp1aus repeats that lyophilised is important. I believe it, but I have never seen anyone show why, and when I search I get 2 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true because…

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7 comments, started 2 years ago
u/ines_lindqvist584 points·2 years ago
well that is my evening gone, thanks for the paper
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u/adaeze_weiss351 points·2 years ago

time-at-temperature integral is the dose, not just peak temperature

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u/asks_dumb_questions260 points·2 years ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/nayeli_iyer0 points·2 years ago

time-at-temperature integral is the dose, not just peak temperature

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/usb_logger_ursulaMOD231 points·2 years ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/fatima_yildiz272 points·2 years ago

This is correct. Dry powder is way more robust than liquid.

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u/intent_to_treat0 points·2 years ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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