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Single comment threadYou are looking at one branch of my eGFR moved and I cannot work out whether lyophilised is why — 51 comments in the full submission. View in context.
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c/coldchain·submitted 2 years ago by u/low_appetite_lisa

my eGFR moved and I cannot work out whether lyophilised is why

Databranch of 8 comments

Genuinely asking, not being difficult. Everyone in c/glp1aus repeats that lyophilised is important. I believe it, but I have never seen anyone show why, and when I search I get 2 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true because…

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8 comments, started 2 years ago
u/kian_solberg868 points·2 years ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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[removed]315 points·2 years ago

[removed by moderator]

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u/low_appetite_lisaOP126 points·2 years ago

The gel pack lasted 10 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.

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u/split_dose_sceptic143 points·2 years ago

lane reports need origin, destination, carrier, and actual transit days

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u/low_appetite_lisaOP111 points·2 years ago·edited

Disagree. What you are describing is consistent with packaging, not with what you concluded.

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u/coldchain_karencold chain48 points·2 years ago

lane reports need origin, destination, carrier, and actual transit days

Disagree on that part. 99.2% and 96.2% on the same vial is normal.

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u/spain_receta281 points·2 years ago·edited

Disagree. What you are describing is consistent with ice pack, not with what you concluded.

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u/low_appetite_lisaOP526 points·2 years ago

France to France takes 24 days on average, variance is 16 days

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Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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