freezing reconstituted product: why the answer is no
packaging. That is the whole post, but I will justify it. Everything else people worry about in c/glp1science is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort packaging out first, and almost nobody does. I say this having got it wrong for 12 months. My ApoB…
Disagree. What you are describing is consistent with lyophilised, not with what you concluded.
customs clearance often breaks the cold chain, factor that in
no tracking numbers, no full addresses, no label photos — instant removal
no tracking numbers, no full addresses, no label photos — instant removal
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
data logger is the standard, gut feeling is not
This is correct. Dry powder is way more robust than liquid.
The gel pack lasted 23 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.
time-at-temperature integral is the dose, not just peak temperature
time-at-temperature integral is the dose, not just peak temperature
Yes, exactly this, and it is the bit that took me 18 weeks to accept.