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c/coa·submitted 3 months ago by u/yusuf_nakamura

what would you tell week-1 you about certificate of analysis

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Confession thread, sort of. I went from 0.5mg to 12.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 17 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have muscle…

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4 comments, started 3 months ago
u/freya_baptista8 points·3 months ago

the method line is doing real work, not just window dressing

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u/yara_antonsen6 points·3 months ago

Water content on the document? That affects your concentration math.

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u/liv_nkemelu3 points·3 months ago

area% is not mass%, and here is exactly why it matters

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u/soren_zamora6 points·3 months ago·edited

The COA I was holding said 96.8% area and I thought it was trash. Turns out the method was solid and the impurity profile was clean.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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