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c/coa·submitted 2 years ago by u/freya_baptista

batch — my 10-week log, condensed into one table

Questionbranch of 13 comments

Posting this because I searched for it and got nothing useful. Setup: 15mg, week 60, constipation present but not ruining anything. I changed exactly one variable — area percent — and tracked it for 6 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I…

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This branch

13 comments, started 2 years ago
u/kavya_verhoeven215 points·2 years ago

Sent one vial to PeptideMeter and VendorInvestigate. 97.9% and 94.2%. Cost me more than the vial did and I would do it again.

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u/cato_achebe103 points·2 years ago

the method line is doing real work, not just window dressing

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u/freya_baptistaOP141 points·2 years ago

The chromatogram trace is where the real information lives. The summary number is just a headline.

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u/halima_boateng66 points·2 years ago

Sent one vial to PeptideMeter and VendorInvestigate.

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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u/zeynep_zielinski27 points·2 years ago

Small correction: the trial was 2 weeks, not 20. Does not change your point but people will quote it.

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u/priya_palacios19 points·2 years ago

Water content on the document? That affects your concentration math.

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u/freya_baptistaOP18 points·2 years ago

Metadata check caught a COA that was created in a browser four months after the analysis date. Not evidence of fraud, but worth flagging to SGN.

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u/chidi_demir5 points·2 years ago·edited

Metadata check caught a COA that was created in a browser four months after the analysis date.

Yes, exactly this, and it is the bit that took me 8 weeks to accept.

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u/laila_yilmaz60 points·2 years ago

Cosigning. The batch number is load-bearing information.

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u/isabela_nilsen71 points·2 years ago

no "is this good?" without saying what the compound and claimed purity are

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u/kavya_verhoeven44 points·2 years ago

no "is this good?" without saying what the compound and claimed purity are

Adding to this: related substances is doing more work than the comment implies.

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u/mikkel_correia29 points·2 years ago

That is net peptide content, not purity. Different number, different meaning.

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u/hassan_chowdhury50 points·2 years ago

the related substances line is where the story is

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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