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c/coa·submitted 2 months ago by u/blunt_coldbox29

COA is the most under-discussed thing in c/semaglutide

Discussionbranch of 6 comments

Posting this because I searched for it and got nothing useful. Setup: 0.25mg, week 28, injection-site soreness present but not ruining anything. I changed exactly one variable — water content — and tracked it for 2 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else…

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6 comments, started 2 months ago
u/teodor_lokken-36 points·2 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/stablecoin_steve1 point·2 months ago

area% is not mass%, and here is exactly why it matters

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u/priya_palacios1 point·2 months ago

No.

Yes, exactly this, and it is the bit that took me 92 weeks to accept.

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u/tuva_aalto1 point·2 months ago·edited

purity and net content are two different numbers, same vial

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u/meera_sandvik1 point·2 months ago

the counterion is part of the mass you paid for

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u/meera_sandvik1 point·2 months ago

No.

Yes, exactly this, and it is the bit that took me 36 weeks to accept.

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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