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Single comment threadYou are looking at one branch of the amylin thing finally clicked for me and I want to write it down — 28 comments in the full submission. View in context.
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c/cagrilintide·submitted 2 years ago by u/plain_titration

the amylin thing finally clicked for me and I want to write it down

Trial Databranch of 5 comments

Genuinely asking, not being difficult. Everyone in c/hplc repeats that satiety is important. I believe it, but I have never seen anyone show why, and when I search I get 24 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true because it has…

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5 comments, started 2 years ago
u/zeynep_duarte523 points·2 years ago

Yeah, amylin is doing different work than GLP-1.

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u/ledger_modMOD265 points·2 years ago·edited

Retitled to remove editorialising. Put the evidence in the body.

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u/lipid_panel_larrybloodwork179 points·2 years ago

The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does cagrilintide.

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u/tomas_kimani58 points·2 years ago

The satiety on amylin analogs is described as physically different.

Adding to this: REDEFINE is doing more work than the comment implies.

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u/mateusz_adebayo142 points·2 years ago

tendon and cagrilintide literature in rodents is interesting

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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