u/yara_bakken
Contributes reviews on supplier material. Based in Recife.
member · joined 12 Mar 2025
Comments — page 3 of 3
comment on week 96 check-in — 26kg down, fatigue manageable, one thing confusing me in c/hplc · 35 points · 1 year ago
axis labels included, always
comment on what would you tell week-1 you about hazard ratio in c/trialwatch · -16 points · 1 year ago
off-label use data is different from approved-indication data
comment on unpopular opinion: integration is massively overrated in c/hplc · 162 points · 1 year ago
Mechanistically the bit that matters is LC-MS. It explains most of the early profile and a decent chunk of the outcome.
comment on [Lab] 4th independent test on BCH, and the trend is the interesting part in c/trialwatch · 95 points · 1 year ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on switched from 10mg to 7.5mg and the fatigue got better, not worse in c/hplc · 212 points · 1 year ago
a round-robin on baseline integration would be genuinely useful
comment on what changed for me between week 95 and week 49 in c/labresults · 8 points · 1 year ago
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
comment on small win: tapering stopped being a problem at week 30 in c/tapering · 4 points · 1 year ago
This is correct. Discontinuation data is real.
comment on Spain: LC-MS, and what it actually costs here in c/hplc · 26 points · 1 year ago
state the method: column, gradient, detection wavelength, injection volume
comment on the STEP question that gets asked weekly, answered properly in c/trialwatch · 75 points · 1 year ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
comment on [Question] how do you actually verify batch in c/labresults · 367 points · 1 year ago
multiple batches from SSA show a spread, that is the data
comment on what would you tell week-1 you about gradient in c/hplc · 29 points · 1 year ago
chromatogram or it did not happen
comment on genuine question about TRIUMPH that I am slightly embarrassed to ask in c/trialwatch · 312 points · 2 years ago
Is that absolute or relative risk reduction?
comment on week 16 check-in — 46kg down, early fullness manageable, one thing confusing me in c/trialwatch · 12 points · 2 years ago
event rates are more informative than hazard ratios alone
comment on stalled for 2 weeks at 7.5mg and I refuse to panic this time in c/labresults · 61 points · 2 years ago
do not editorialise in the title, put the number in the title and the opinion in the body
comment on method development vs HPLC — genuinely asking which matters more in c/hplc · 7 points · 2 years ago
the detector wavelength matters more than people think
comment on does test results actually matter or is it forum lore at this point in c/labresults · 58 points · 2 years ago
the 98.7% result confirmed the vendor claim, that is the signal
comment on is it normal to get early fullness at week 15 in c/labresults · 96 points · 2 years ago
reship and retest is the honest way to handle a low result
comment on am I the only one who found integration harder than the injections in c/hplc · 9 points · 2 years ago
integration decision on a shoulder changes your number by half a point on its own
Disagree on that part. 99.2% and 99.3% on the same vial is normal.