Week 66 update. 22kg down from the start, muscle cramps basically gone since about week 11. Things that worked: consistency, protein at breakfast, walking more than I…
u/yannick_salinas
Contributes reviews on supplier material. Based in Ilorin.
member · joined 16 Jul 2025
Overview — page 4 of 5
comment on someone explain glucagon to me like I have not read a paper in years in c/retatrutide · 16 points · 1 year ago
Slight fix: the number was 99.1, not 99.0. Decimal point, but a fairly consequential one.
comment on the SELECT thing finally clicked for me and I want to write it down in c/trialwatch · 212 points · 1 year ago
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
comment on the SELECT thing finally clicked for me and I want to write it down in c/trialwatch · 394 points · 1 year ago
Not to be pedantic but SURMOUNT and STEP are being used interchangeably and they are not interchangeable in real life.
comment on basics vs what is — genuinely asking which matters more in c/newbiequestions · 0 points · 1 year ago
Not convinced. The evidence does not support that reading.
comment on basics vs what is — genuinely asking which matters more in c/newbiequestions · 48 points · 1 year ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on basics vs what is — genuinely asking which matters more in c/newbiequestions · 73 points · 1 year ago
Titration means going slow. The 10mg is the starter, not the dose you stay on, not the dose you need to feel it.
Genuinely asking, not being difficult. Everyone in c/meta repeats that normal is important. I believe it, but I have never seen anyone show why, and when I search I get…
comment on genuine question about amylin that I am slightly embarrassed to ask in c/cagrilintide · 4 points · 1 year ago
the amylin agonist pool is small, community is satiety
comment on what changed for me between week 20 and week 69 in c/newbiequestions · 25 points · 1 year ago
Yeah, that is totally normal for week 9.
comment on [Results] 21 weeks on 2.4mg, full numbers, ask me anything boring in c/retatrutide · 11 points · 1 year ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on [Vendor] WXT order #23 — France, 9 days, no drama, receipts inside in c/trialwatch · 1 points · 1 year ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
comment on [Vendor] WXT order #23 — France, 9 days, no drama, receipts inside in c/trialwatch · 40 points · 1 year ago
Which trial and what was the primary endpoint?
Quick one. Canada here. SURPASS works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
comment on switched from 2.5mg to 10mg and the early fullness got better, not worse in c/retatrutide · 73 points · 1 year ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Question] how do you actually verify week one in c/newbiequestions · 58 points · 1 year ago
what is bac water — bacteriostatic water, preservative included
Yes, exactly this, and it is the bit that took me 62 weeks to accept.
comment on week 96 check-in — 37kg down, early fullness manageable, one thing confusing me in c/newbiequestions · 14 points · 1 year ago
Pens or research vials?
comment on three years of SURMOUNT threads, summarised so you do not have to read them in c/trialwatch · 20 points · 1 year ago
press release TRIUMPH posts must be flaired until a publication exists
comment on three years of SURMOUNT threads, summarised so you do not have to read them in c/trialwatch · 116 points · 1 year ago
the relative risk reduction in headlines is not the whole story
comment on three years of SURMOUNT threads, summarised so you do not have to read them in c/trialwatch · 19 points · 1 year ago
Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.