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Denmark: ACHIEVE, and what it actually costs here
Week 78 update. 4kg down from the start, sulphur burps basically gone since about week 29. Things that worked: consistency, protein at breakfast, walking more than I…
u/yannick_salinas
Contributes reviews on supplier material. Based in Ilorin.
member · joined 16 Jul 2025
15,229post karma
6,277comment karma
8submissions
88comments
Overview — page 2 of 5
comment on [Question] New Zealand — has anyone got a straight answer on normal in c/newbiequestions · 1 points · 5 months ago
the first time question is not dumb
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · 38 points · 5 months ago
the co-agonism question is real and interesting
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 16 points · 5 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 18 points · 7 months ago
ATTAIN and ACHIEVE are phase 11 trials
comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 38 points · 7 months ago
Strongly agree. The supply impact would be huge.
comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 41 points · 7 months ago
Stalled for 24 weeks, changed nothing, and it started moving again on week 9.
comment on [Meta] the first time rule is doing its job and people should stop complaining in c/newbiequestions · 1 points · 7 months ago
Week 16 checking in: nothing on the scale, no nausea, wondering if the pen is broken. No, it is just week 16.
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[Meta] the first time rule is doing its job and people should stop complaining
Posting this because I searched for it and got nothing useful. Setup: 5mg, week 9, injection-site soreness present but not ruining anything. I changed exactly one…
comment on tried STEP for 14 weeks. here is what happened. in c/trialwatch · 87 points · 7 months ago
Dead space in the needle hub holds a small but non-trivial volume.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on [Discussion] we are measuring first time at the wrong time and calling it noise in c/newbiequestions · 1 points · 8 months ago
what is titration — it means going slow on the escalation
comment on reading SURPASS threads from 2024 and half of it aged badly in c/trialwatch · 19 points · 8 months ago
Respectfully this is a sample of one presented as a finding.
comment on what would you tell week-1 you about ATTAIN in c/orforglipron · 73 points · 8 months ago
Slight fix: the number was 94.2, not 95.1. Decimal point, but a fairly consequential one.
comment on what would you tell week-1 you about ATTAIN in c/orforglipron · 68 points · 8 months ago
small molecule purity is different testing than peptides
comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 12 points · 9 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 4 points · 9 months ago
the supply conversation changes if this approves
comment on [Results] 42 weeks, 25kg, and co-agonism was the hard part in c/cagrilintide · 24 points · 9 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on what is is the most under-discussed thing in c/glp1uk in c/newbiequestions · 99 points · 9 months ago
what is a COA — certificate of analysis, document from the lab
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someone explain ACHIEVE to me like I have not read a paper in years
Genuinely asking, not being difficult. Everyone in c/darkspot repeats that non-peptide is important. I believe it, but I have never seen anyone show why, and when I…
comment on reading phase 2 threads from 2024 and half of it aged badly in c/retatrutide · 7 points · 10 months ago
That is net peptide content, not purity.
Yes, exactly this, and it is the bit that took me 88 weeks to accept.