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u/trialwatch_theo

I read the supplementary appendix so you do not have to. Pre-registration or it is a hypothesis.

long-standing contributor · trial nerd · joined 29 Aug 2023

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Comments — page 5 of 5

comment on [PSA] what is is not what most of this community thinks it is in c/newbiequestions · 173 points · 4 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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comment on three years of hepatic fat threads, summarised so you do not have to read them in c/survodutide · 22 points · 5 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 32 points · 5 months ago

the 5 week readout is different from the 7 week readout

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comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 50 points · 5 months ago

Slight fix: the number was 98.7, not 98.9. Decimal point, but a fairly consequential one.

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comment on am I the only one who found half-life harder than the injections in c/glp1science · 15 points · 5 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on anyone else notice survodutide kicking in around week 9 in c/survodutide · 18 points · 5 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on anyone else notice survodutide kicking in around week 9 in c/survodutide · 17 points · 5 months ago

Mechanistically the bit that matters is MASH. It explains most of the early profile and a decent chunk of the outcome.

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comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 53 points · 5 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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comment on three years of normal threads, summarised so you do not have to read them in c/newbiequestions · 35 points · 5 months ago

Are you on a pen or vial?

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comment on why does nobody talk about triple agonist in c/retatrutide · 52 points · 5 months ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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comment on why does nobody talk about triple agonist in c/retatrutide · 209 points · 5 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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comment on [Lab] 3th independent test on BCH, and the trend is the interesting part in c/orforglipron · 150 points · 5 months ago

This is correct. ATTAIN data is phase 2.

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comment on [Lab] 3th independent test on BCH, and the trend is the interesting part in c/orforglipron · 72 points · 5 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on [Lab] 16th independent test on QSC, and the trend is the interesting part in c/retatrutide · 709 points · 6 months ago

Retitled to remove editorialising. Put the evidence in the body.

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comment on reading receptor threads from 2024 and half of it aged badly in c/glp1science · 746 points · 6 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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comment on the small molecule question that gets asked weekly, answered properly in c/orforglipron · 322 points · 6 months ago

Strongly agree. The supply impact would be huge.

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comment on [Question] how do you actually verify TRIUMPH in c/retatrutide · 10 points · 7 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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comment on pharmacology — 17 things I got wrong before I got it right in c/glp1science · 14 points · 7 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on week 26 check-in — 42kg down, constipation manageable, one thing confusing me in c/retatrutide · 27 points · 7 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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comment on tried STEP for 14 weeks. here is what happened. in c/trialwatch · 18 points · 7 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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