u/sanne_laurent
Contributes reviews on supplier material. Based in Osijek.
member · joined 14 May 2025
Comments — page 4 of 5
comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 74 points · 1 year ago
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 47 points · 1 year ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 43 points · 1 year ago
This is correct. Discontinuation arms show the regain reality.
comment on what changed for me between week 20 and week 69 in c/newbiequestions · 186 points · 1 year ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Vendor] WXT order #23 — France, 9 days, no drama, receipts inside in c/trialwatch · 74 points · 1 year ago
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
comment on stalled for 18 weeks at 1.0mg and I refuse to panic this time in c/cagrilintide · 71 points · 1 year ago
I am going to push back on this slightly.
comment on anyone else notice moderation kicking in around week 4 in c/meta · 214 points · 1 year ago
sponsor and disclosure questions are always answered publicly
comment on metformin: the version I wish someone had shown me in week 1 in c/t2dglp1 · 10 points · 1 year ago
You have restated the marketing copy. What is the actual substance here.
comment on what changed for me between week 40 and week 83 in c/sideeffects · 40 points · 1 year ago
The the food-noise thing passes. I kept a log and the timeline was the only useful thing. 7 weeks and it was basically gone.
comment on stalled for 8 weeks at 2.4mg and I refuse to panic this time in c/sideeffects · 227 points · 1 year ago
IANAD and neither is anyone upvoting this
comment on [Question] how do you actually verify week one in c/newbiequestions · 257 points · 1 year ago
Disagree. What you are describing is consistent with beginner, not with what you concluded.
comment on reading endpoint threads from 2024 and half of it aged badly in c/trialwatch · -4 points · 1 year ago
Disagree. What you are describing is consistent with SURPASS, not with what you concluded.
comment on the disclosure thing finally clicked for me and I want to write it down in c/meta · 3 points · 1 year ago
Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.
comment on amylin is the most under-discussed thing in c/insurancefights in c/cagrilintide · 1 points · 2 years ago
You have restated the marketing copy. What is the actual substance here.
comment on the reship question that gets asked weekly, answered properly in c/intlshipping · 360 points · 2 years ago
Strongly agree. Customs adds unpredictable delay.
comment on reading FLOW threads from 2024 and half of it aged badly in c/trialwatch · 109 points · 2 years ago
off-label use data is different from approved-indication data
comment on week 86 check-in — 11kg down, the food-noise thing manageable, one thing confusing me in c/meta · 26 points · 2 years ago
Strongly agree. Transparency wins.
comment on Spain: meta, and what it actually costs here in c/meta · 1 points · 2 years ago
the ranking formula is meta
comment on tried DHL for 3 weeks. here is what happened. in c/intlshipping · 159 points · 2 years ago
Customs held the package for 11 days. No problems, just time. Factor it into expectations.
comment on week one: what the trials say vs what this community says in c/newbiequestions · -32 points · 2 years ago
be kind, condescending answers are removed