u/ferritin_low

Strongly agree. Step therapy is predictable if you have the criteria.

name your province, coverage is provincial

Did the nausea start before or after the dose increase?

This is the "correlation is mechanism" thing again. You changed three variables at once.

Half-life is about 168 hours, so steady state lands around week 11–5.

Adding to this: formulary is doing more work than the comment implies.

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

long-acting amylin is co-agonism, different satiety profile

denial reason codes matter, ask for the actual code

the reflux passes. i promise. not medical advice.

not approved anywhere, keep posts descriptive, not instructional

Hard agree. Week 82 me needed this. Week 33 me is nodding smugly.

This matches the trial data. SURMOUNT-1 was 98.0% body weight at 5 weeks.

The fatigue was genuinely awful for three weeks and then simply stopped. Week 53 me did not think I would make it to week 10.

This matches the trial data. SURMOUNT-1 was 99.2% body weight at 20 weeks.

Tried both. Sema worked, tirz worked better for me, but my sulphur burps profile was worse on tirz.

The dual agonism story is real. The appetite is physically different from semaglutide alone.

Half-life is about 168 hours, so steady state lands around week 24–5.

Adding to this: lowest effective dose is doing more work than the comment implies.

How long at each step before you escalated?

Is that on Mounjaro pens or research tirzepatide?