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c/tirzepatide·submitted 1 year ago by u/santiago_villalobos

Germany: SURMOUNT, and what it actually costs here

Discussionbranch of 10 comments

Right, the Mounjaro question again, but with numbers this time. I have 4 data points over 24 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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10 comments, started 1 year ago
u/tove_vasquez624 points·1 year ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/ingrid_correia507 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/halima_boateng414 points·1 year ago

the 15mg is the top of the pen, not the required dose

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u/sten_bhattacharya191 points·1 year ago

How long at each step before you escalated?

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u/rania_diallo-9 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/matias_salgado1 point·1 year ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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u/santiago_villalobosOP0 points·1 year ago

the early fullness from tirz is different, not necessarily worse

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u/halima_boateng1 point·1 year ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/fatima_wojcik1 point·1 year ago

do not crack the pen, we have been over this

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u/matias_salgado1 point·1 year ago

Strongly agree. Tirz is better than sema is not a claim without a comparator dose.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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