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c/tirzepatide·submitted 1 months ago by u/tove_vasquez

[Question] how do you actually verify Mounjaro

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Confession thread, sort of. I went from 0.25mg to 10mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have constipation…

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4 comments, started 1 months ago
u/bastian_eriksen11 points·1 months ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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u/signe_villalobos4 points·1 months ago

How long at each step before you escalated?

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u/nabila_ogunleye2 points·1 months ago

the dual agonism hits different and that is why people describe it differently

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u/ahmed_iyer1 point·1 months ago

Hard agree. The food noise disappears differently on the two compounds.

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Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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