[Discussion] can we stop arguing about tirzepatide until somebody posts a number
Trying to settle this properly because the thread from last year went in circles. The claim: tirzepatide matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 4 months without either producing anything. What would actually settle it is 3 people measuring the same…
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
the appetite change on tirz is more than just reduced hunger, it is different machinery
the GIP side does different things than the GLP-1 side, that is the point
SURMOUNT data is messier than STEP data but the weight loss is there
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
do not crack the pen, we have been over this
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
the 15mg is the top of the pen, not the required dose
Strongly agree.
Adding to this: Mounjaro is doing more work than the comment implies.