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c/tirzepatide·posted 6 months ago by u/nabila_ogunleye

genuine question about SURPASS that I am slightly embarrassed to ask

Lab

Right, the SURPASS question again, but with numbers this time.

I have 10 data points over 22 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 7, not week 56. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

0 up / 0 down41% upvoted7 commentsid 1uv3q629 Jan 2026

7 comments

7 in this archive, depth 4

best — the order this archive was captured in

u/britt_okwuosa4 points·6 months ago

Crossposting this to c/glp1women because the people who need it are not reading this community.

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u/nabila_ogunleyeOP2 points·6 months ago

Vial-splitting is on-topic here. Do not ask about pen-cracking, that goes in c/reconstitution.

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u/britt_okwuosa1 point·6 months ago

the 15mg is the top of the pen, not the required dose

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u/sten_bhattacharya1 point·6 months ago

How long at each step before you escalated?

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u/b12_baseline1 point·6 months ago

do not crack the pen, we have been over this

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u/nabila_ogunleyeOP3 points·6 months ago

Is that on Mounjaro pens or research tirzepatide?

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u/marta_dziedzic1 point·6 months ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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