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c/tirzepatide·submitted 7 months ago by u/dario_stanescu

what changed for me between week 80 and week 34

Labbranch of 5 comments

Week 35 update. 16kg down from the start, reflux basically gone since about week 75. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux. The part that surprised me is how much of this is admin. Ordering,…

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5 comments, started 7 months ago
u/titration_marshalMOD5 points·7 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/sten_palacios4 points·7 months ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/kaia_wojcik3 points·7 months ago

The dual agonism story is real. The appetite is physically different from semaglutide alone.

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u/laila_yilmaz3 points·7 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/emil_wojcik2 points·7 months ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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