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c/tirzepatide·submitted 7 months ago by u/dario_stanescu

what changed for me between week 80 and week 34

Labbranch of 5 comments

Week 35 update. 16kg down from the start, reflux basically gone since about week 75. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux. The part that surprised me is how much of this is admin. Ordering,…

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5 comments, started 7 months ago
u/zaid_balogun8 points·7 months ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/emil_barros2 points·7 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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[removed]1 point·7 months ago

[removed by moderator]

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u/amara_halonen1 point·7 months ago

do not crack the pen, we have been over this

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u/ahmed_iyer-14 points·7 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

Adding to this: Mounjaro is doing more work than the comment implies.

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Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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