GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of SURPASS — 5 things I got wrong before I got it right — 40 comments in the full submission. View in context.
1.9k
c/tirzepatide·submitted 8 months ago by u/ghrp_history

SURPASS — 5 things I got wrong before I got it right

Titrationbranch of 6 comments

Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 12 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have…

Read the full submission and all 40 comments →

This branch

6 comments, started 7 months ago
u/marit_sandvik59 points·7 months ago

week 67 on Mounjaro and the appetite profile is genuinely different from sema

replysharereportpermalink
u/kaia_wojcik32 points·7 months ago

Slight fix: the number was 98.7, not 98.6. Decimal point, but a fairly consequential one.

replysharereportpermalink
u/sten_palacios15 points·7 months ago

My ALT moved faster on tirz than on sema at the same timepoint, which matches what people report.

replysharereportpermalink
u/blunt_coldbox295 points·7 months ago·edited

the reflux from tirz is different, not necessarily worse

replysharereportpermalink
load more comments (2) →

← back to the whole thread

About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

187kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.comSponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
More in c/tirzepatide
c/tirzepatide rules
  1. "Tirz is better than sema" needs a comparator dose or it is a vibe, not a claim.
  2. Vial-splitting and self-compounding discussion stays in c/reconstitution.
  3. No pen-cracking tutorials. Discussing that people do it is fine; instructions are not.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/titration_marshalu/incretin_ivyu/quiet_moderatoru/dexa_twice_yearly
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →