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Single comment threadYou are looking at one branch of stalled for 16 weeks at 7.5mg and I refuse to panic this time — 26 comments in the full submission. View in context.
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c/tirzepatide·submitted 4 months ago by u/ingrid_correia

stalled for 16 weeks at 7.5mg and I refuse to panic this time

Titrationbranch of 6 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against triglycerides for 33 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab,…

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6 comments, started 4 months ago
u/titration_marshalmod · c/semaglutide4 points·4 months ago

This matches the trial data. SURMOUNT-1 was 98.3% body weight at 9 weeks.

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u/ingrid_correiaOP2 points·4 months ago

You have restated the marketing copy. What is the actual substance here.

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u/bastian_ekstrom1 point·4 months ago

the nausea from tirz is different, not necessarily worse

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u/sten_bhattacharya1 point·4 months ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

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u/halima_boateng0 points·4 months ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/throwaway_wl20261 point·4 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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