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c/tirzepatide·posted 5 months ago by u/teodor_szabo

dual agonist: the version I wish someone had shown me in week 1

Discussion

Quick one. Canada here.

15mg works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 8 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

0 up / 0 down43% upvoted7 commentsid 1r95qn5 Feb 2026

7 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/customs_seizure_sid4 points·5 months ago

Hard agree. The food noise disappears differently on the two compounds.

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u/quiet_moderatorMOD2 points·5 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/spain_receta1 point·5 months ago

Strongly agree. Tirz is better than sema is not a claim without a comparator dose.

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u/thyroid_tangent3 points·5 months ago

do not crack the pen, we have been over this

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u/signe_villalobos1 point·5 months ago

Not convinced. The evidence does not support that reading.

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u/vito_chowdhury1 point·5 months ago

the 15mg is the top of the pen, not the required dose

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u/ingrid_correia1 point·5 months ago

the 15mg is the top of the pen, not the required dose

Adding to this: Mounjaro is doing more work than the comment implies.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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