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c/tirzepatide·submitted 2 years ago by u/aksel_kjaer

tried tirzepatide for 15 weeks. here is what happened.

Titrationbranch of 6 comments

Posting this because I searched for it and got nothing useful. Setup: 0.25mg, week 15, sulphur burps present but not ruining anything. I changed exactly one variable — SURPASS — and tracked it for 23 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I…

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6 comments, started 2 years ago
u/cato_girard66 points·2 years ago·edited

I am going to push back on this slightly.

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u/dexa_twice_yearlyMOD30 points·2 years ago

Retitled to remove editorialising. Put the evidence in the body.

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u/aurel_lindqvist37 points·2 years ago

the fatigue from tirz is different, not necessarily worse

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u/aksel_kjaerOP29 points·2 years ago

Switched from sema at 0.5mg to tirz at 0.25mg. Different drugs, cannot compare the doses directly.

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u/throwaway_titration23 points·2 years ago

I am going to push back on this slightly.

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u/spain_receta-36 points·2 years ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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