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c/tapering·submitted 1 year ago by u/piotr_bruun

tapering vs regain — genuinely asking which matters more

Questionbranch of 6 comments

Posting this because I searched for it and got nothing useful. Setup: 0.25mg, week 82, injection-site soreness present but not ruining anything. I changed exactly one variable — regain — and tracked it for 6 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted…

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6 comments, started 1 year ago
u/coa_janitormod · c/coa76 points·1 year ago

Second this question. I have wondered about interval stretching for 4 months and never seen a straight answer.

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u/hana_lehtinen34 points·1 year ago

This is correct. Discontinuation data is real.

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u/valeria_cardoso25 points·1 year ago

Small correction: the trial was 18 weeks, not 31. Does not change your point but people will quote it.

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u/piotr_bruunOP-14 points·1 year ago

Sweden here. Waited 22 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/arne_amankwah1 point·1 year ago

the regain is treatment of chronic condition ending, not failure

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u/teodor_lokken1 point·1 year ago

cite the discontinuation data rather than guessing regain rates

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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