[Question] Australia — has anyone got a straight answer on hepatic fat
Genuinely asking, not being difficult.
Everyone in c/tirzepatide repeats that biopsy is important. I believe it, but I have never seen anyone show why, and when I search I get 8 threads of people agreeing with each other.
Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?
I am not trying to be the "source?" guy. I would just like a source.
best — the order this archive was captured in
Strongly agree. The safety story is separate.
Removed a chain here. The rule is one line long and it is not negotiable.
Yeah, glucagon co-agonism is genuinely different.
glucagon co-agonism has a different safety story
glucagon co-agonism has a different safety story
Adding to this: hepatic fat is doing more work than the comment implies.
MASH claims need the trial and the biopsy endpoint
Yeah, glucagon co-agonism is genuinely different.
rodent survodutide is investigation only
glucagon injection is a different vector than GLP-1
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
Yeah, glucagon co-agonism is genuinely different.
The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.
The thing nobody prepared me for was the quiet.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
the safety profile is not just tirzepatide amplified
The thing nobody prepared me for was the quiet.
Adding to this: biopsy is doing more work than the comment implies.
Week 22 for me and the honest summary is: 11kg down, muscle cramps manageable, and I have thought about food maybe four times today.
Poland here. Waited 15 months on a list, gave up, went private, and the total cost was roughly what I expected.
The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.
the heart rate signal is real in the data
Poland here.
Yes, exactly this, and it is the bit that took me 20 weeks to accept.
Poland here.
Disagree on that part. 97.9% and 97.6% on the same vial is normal.
This is correct. Do not generalise from tirzepatide.
the safety profile is not just tirzepatide amplified
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
- 1Yeah, glucagon co-agonism is genuinely different.11 comments in this branch · started by u/kasper_cabrera
- 2Poland here. Waited 15 months on a list, gave up, went private, and the…8 comments in this branch · started by u/nadia_kjaer