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c/sideeffects·posted 2 months ago by u/zeynep_zielinski

sulphur burps is the most under-discussed thing in c/orforglipron

Discussion Clean Column ×6 The Quiet One ×2

Confession thread, sort of.

I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 19 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have sulphur burps I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 92 reads it before doing the same thing.

2,382 up / 353 down87% upvoted50 commentsid 1bb8n13 May 2026

50 comments

26 in this archive, depth 5

best — the order this archive was captured in

u/laila_delgado177 points·2 months ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/fabio_nkemelu124 points·2 months ago

Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.

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u/janoshik_junkieindependent tester66 points·2 months ago

Yeah, the injection-site soreness hit on day 6 for me too, not day 1.

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u/britt_abubakar33 points·2 months ago

nausea on day 2 is normal, nausea after week 75 is worth checking

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u/cesar_oyelaran-14 points·2 months ago

How many weeks in are you? 7 weeks is noise, 20 weeks is a trend.

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u/bastian_eriksen1 point·2 months ago

I am going to push back on this slightly.

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u/hassan_castellanos1 point·2 months ago

early fullness at 7.5mg is different from 5mg

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u/marit_coelho1 point·2 months ago

This is correct. The nausea is horrible for three weeks and then just ends.

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u/tomas_broberg1 point·2 months ago

early fullness at 2.5mg is different from 1.0mg

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u/aurel_mwangi88 points·2 months ago

Disagree. What you are describing is consistent with nausea, not with what you concluded.

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u/elin_lundgren59 points·2 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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[removed]44 points·2 months ago

[removed by moderator]

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u/nabila_ogunleye28 points·2 months ago

Is that before or after you stabilized your heart rate?

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u/constipation_clubMOD45 points·2 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/placebo_arm_pam12 points·2 months ago

severe abdominal pain is an urgent-care question, not a forum question

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u/ayesha_erdogan6 points·2 months ago

the food-noise thing stops around week 67 for most people

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u/sequence_checkerresearch peptides33 points·2 months ago

IANAD and neither is anyone upvoting this

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u/adaeze_brandt13 points·2 months ago

IANAD and neither is anyone upvoting this

Adding to this: fatigue is doing more work than the comment implies.

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u/coring_the_stopper19 points·2 months ago

hair loss is real and usually reversible when you stabilize

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u/cesar_oyelaran17 points·2 months ago

Resting heart rate up 4 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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