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c/semaglutide·posted 5 months ago by u/plain_titration

[PSA] titration is not what most of this community thinks it is

PSA Cold Box ×1 Long Haul ×2 Receipts ×2

Quick one. Canada here.

Wegovy works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 18 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

26,261 up / 19,097 down58% upvoted14 commentsid cv4yqz10 Feb 2026

14 comments

10 in this archive, depth 4

best — the order this archive was captured in

u/oskar_kaufmann614 points·5 months ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/zeynep_zielinski356 points·5 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/adaeze_brandt260 points·5 months ago

Strongly agree. If it is not working at 1.0mg after 74 weeks, going up is not automatically the answer.

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u/b12_baseline68 points·5 months ago

okay but what dose of sema are you on

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u/rafael_ostergaard28 points·5 months ago

okay but what dose of sema are you on

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/kavya_radich210 points·5 months ago
oh thank god it is not just me
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u/iman_falk131 points·5 months ago

This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.

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[deleted]92 points·5 months ago

[deleted]

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u/teodor_duarte43 points·5 months ago

[deleted]

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/greta_perrin-29 points·5 months ago

okay but what dose of sema are you on

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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