[Meta] proposal — a flair for plateau posts
Genuinely asking, not being difficult.
Everyone in c/coldchain repeats that titration is important. I believe it, but I have never seen anyone show why, and when I search I get 23 threads of people agreeing with each other.
Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?
I am not trying to be the "source?" guy. I would just like a source.
best — the order this archive was captured in
okay but what dose of sema are you on
Sceptical. If this were true we would see it reflected in the data and we do not.
week 13 on the pen, 29kg down, this is the answer
week 13 and i am still not at maintenance, do not rush the ladder
I did the fast version. 15mg to 0.25mg in 12 weeks. Spent a weekend learning why the schedule exists.
pens are overpriced, research vials are research grade, same molecule different price
Slight fix: the number was 96.8, not 94.2. Decimal point, but a fairly consequential one.
This is what I tell everyone in c/newbiequestions and they never believe me until week 46.
the quiet is real. the food noise just stops.
Hard agree. Week 89 me needed this. Week 37 me is nodding smugly.
the injection-site soreness passes. i promise. not medical advice.
stalled at 15mg, went up, and regretted it, the stall would have broken anyway
the the food-noise thing passes. i promise. not medical advice.
I did the fast version. 10mg to 1.7mg in 19 weeks. Spent a weekend learning why the schedule exists.
Mechanistically the bit that matters is titration. It explains most of the early profile and a decent chunk of the outcome.
Mechanistically the bit that matters is titration.
Disagree on that part. 97.9% and 97.6% on the same vial is normal.
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
my eGFR moved before the scale did and i nearly missed it
- 1okay but what dose of sema are you on7 comments in this branch · started by u/sorted_by_new
- 2This is what I tell everyone in c/newbiequestions and they never believe me…5 comments in this branch · started by u/tomas_kimani