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why does nobody talk about secretagogue

Question Long Haul ×8 Cold Box ×3

Been lurking in c/cagrilintide for about 15 months and finally have something worth posting.

Short version: week 39, 2.5mg, and secretagogue is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 23 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 33.

2,507 up / 264 down90% upvoted54 commentsid 1lqq0j27 Oct 2024

54 comments

28 in this archive, depth 5

best — the order this archive was captured in

u/runa_grimaldi392 points·1 year ago

thymosin fragments, GH secretagogues, secretagogue, long tail

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u/old_account_2023468 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/second_week_sceptic121 points·1 year ago

This is correct. Name it precisely.

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u/viktor_erdogan-7 points·1 year ago

evidence-level statements required: in vitro, rodent, or human

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u/cesar_oyelaran325 points·1 year ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/rui_only_roMOD194 points·1 year ago

Retitled to remove editorialising. Put the evidence in the body.

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u/ahmed_fonseca251 points·1 year ago

How many weeks between the two measurements?

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u/ahmed_cardoso205 points·1 year ago·edited

How many weeks between the two measurements?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/tuva_iyer103 points·1 year ago

the 13-letter analogs are speculative

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u/coa_forgery_watch147 points·1 year ago

focus on identity verification, handling, evidence state

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u/marisol_frisk48 points·1 year ago

the thymosin literature is thin on humans

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u/santiago_rasmussen33 points·1 year ago

the thymosin literature is thin on humans

Adding to this: handling is doing more work than the comment implies.

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u/cold_chromatogram_only115 points·1 year ago

name the compound precisely, TB-500 and Thymosin Beta-4 are not the same

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u/hplc_hobbyistruns their own column154 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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[deleted]58 points·1 year ago

[deleted]

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u/crp_curious20 points·1 year ago

Second this question. I have wondered about research peptides for 24 months and never seen a straight answer.

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u/hassan_ostergaard125 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/tired_ledger_notes77 points·1 year ago

not approved for human use, full stop

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u/vendorinvestigate_vicOP62 points·1 year ago

This is correct. Name it precisely.

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u/elin_trevino23 points·1 year ago·edited

everything else in the vial drawer, identity

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u/vendorinvestigate_vic16 points·1 year ago

everything else in the vial drawer, thymosin

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u/tidy_vialdrawer_pls101 points·1 year ago
genuinely useful, thanks
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u/ledger_modmod · vetting82 points·1 year ago·edited

focus on identity verification, handling, evidence state

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About c/researchpeptides

The wider research-peptide catalogue: thymosin fragments, GH secretagogues, melanocortin agonists, and the long tail of three-letter analogs. Focus on identity verification, handling and the state of the evidence — not on protocols, because these are not approved for human use.

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