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c/reconstitution·submitted 2 years ago by u/elin_ferrari

why does nobody talk about reconstitution

PSAbranch of 7 comments

Trying to settle this properly because the thread from last year went in circles. The claim: mg/mL matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 9 months without either producing anything. What would actually settle it is 13 people measuring the same…

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7 comments, started 2 years ago
u/marisol_frisk54 points·2 years ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/priya_weiss20 points·2 years ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/swirl_dont_shakereconstitution15 points·2 years ago

never post a calculation as advice without stating the concentration

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u/rosa_mensah12 points·2 years ago

more water means more units for the same dose, which means finer resolution

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u/viktor_kirchner7 points·2 years ago

swirl, do not shake, or you are courting oxidation

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u/iman_falk33 points·2 years ago

That is net peptide content, not purity. Different number, different meaning.

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u/saskia_mwangi23 points·2 years ago

stopper coring on the 8th draw because you keep using the same entry point. rotate.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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