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c/reconstitution·posted 2 years ago by u/reflux_report

small win: units stopped being a problem at week 16

Discussion Receipts ×4 Cold Box ×2 Long Haul ×3

Week 57 update. 28kg down from the start, early fullness basically gone since about week 2.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

5,027 up / 1,129 down82% upvoted54 commentsid 1ipoqc26 Dec 2023

54 comments

22 in this archive, depth 4

best — the order this archive was captured in

u/arto_falk463 points·2 years ago

Not convinced. The evidence does not support that reading.

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[removed]172 points·2 years ago

[removed by moderator]

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u/tl_dr_tina55 points·2 years ago

more water means more units for the same dose, which means finer resolution

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u/units_not_mgMOD284 points·2 years ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/emil_okwuosa410 points·2 years ago

30mg vial, 2mL water, concentration is 30/2 — write it on the vial afterwards

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u/emil_wojcik203 points·2 years ago

dead space is real and the syringe matters

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u/gradient_goblin488 points·2 years ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/reflux_reportOP209 points·2 years ago

Cored the stopper on my 19th draw because I kept using the same entry point. Rotate the puncture site.

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u/quarter_dose_queenlow and slow147 points·2 years ago

stopper coring on the 16th draw because you keep using the same entry point. rotate.

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u/sigrid_kaufmann134 points·2 years ago

Removed a chain here.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/yusuf_nakamura188 points·2 years ago

Cored the stopper on my 3th draw because I kept using the same entry point. Rotate the puncture site.

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u/ruben_cabrera49 points·2 years ago

Reconstituted at 3mL when I meant 8mL. Caught it because the units looked wrong. Write the concentration.

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u/santiago_ndiaye0 points·2 years ago

Reconstituted at 3mL when I meant 8mL.

Adding to this: units is doing more work than the comment implies.

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u/iman_falk149 points·2 years ago

the concentration on the vial in marker is the most important step

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u/cardio_endpoint_c217 points·2 years ago

Is that 15mg vial or 38mg?

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u/swirl_dont_shakereconstitution92 points·2 years ago

Not convinced. The evidence does not support that reading.

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u/reflux_reportOP38 points·2 years ago

Is that 30mg vial or 15mg?

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u/yusuf_achebe73 points·2 years ago

dead space is real and the syringe matters

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u/oskar_kaufmann22 points·2 years ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/freya_onwuka49 points·2 years ago·edited

dead space is real and the syringe matters

Adding to this: insulin syringe is doing more work than the comment implies.

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u/saskia_rahimi38 points·2 years ago

5mg vial, 2mL water, concentration is 5/2 — write it on the vial afterwards

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u/yusuf_nakamura10 points·2 years ago

dead space is real and the syringe matters

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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