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c/reconstitution·posted 2 months ago by u/adaeze_cabrera

the units thing finally clicked for me and I want to write it down

Explainer

Something I noticed reading old threads that I have not seen said out loud.

The advice on reconstitution in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

170 up / 8 down95% upvoted20 commentsid 18acgj29 May 2026

20 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/cardio_endpoint_c13 points·2 months ago

Cored the stopper on my 9th draw because I kept using the same entry point. Rotate the puncture site.

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[removed]9 points·2 months ago

[removed by moderator]

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u/india_generic_g13 points·2 months ago

u-100 syringe, not u-40, or your math is off by factor of 9

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u/adaeze_cabreraOP10 points·2 months ago

Two vials, two different concentrations, forgot which was which, almost made a 14 times error. Now I label everything.

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u/sock_puppet_spotter15 points·2 months ago

stopper coring on the 16th draw because you keep using the same entry point. rotate.

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u/ledger_modmod · vetting4 points·2 months ago

5mg vial, 1mL water, concentration is 5/1 — write it on the vial afterwards

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u/arto_falk12 points·2 months ago

Dead space ate 6 units on a low-volume draw. Tiny impact at 0.25mg, massive impact at 15mg.

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u/declared_value_dv7 points·2 months ago
saved. thank you.
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u/yusuf_achebe10 points·2 months ago

You have restated the marketing copy. What is the actual substance here.

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u/adaeze_cabreraOP8 points·2 months ago

Disagree. What you are describing is consistent with concentration, not with what you concluded.

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u/erez_perrin8 points·2 months ago

never post a calculation as advice without stating the concentration

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u/ledger_modmod · vetting6 points·2 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/rasmus_kuipers3 points·2 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/bac_water_banditMOD2 points·2 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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c/reconstitution rules
  1. Show your numbers. "How many units?" with no mg and no mL cannot be answered.
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