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c/reconstitution·submitted 11 months ago by u/piotr_bruun

dead space: what the trials say vs what this community says

Discussionbranch of 9 comments

Quick one. Canada here. dead space works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 7 weeks and cost roughly what I expected. The admin was worse than the…

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9 comments, started 11 months ago
u/saskia_mwangi0 points·11 months ago

Half-life is about 168 hours, so steady state lands around week 10–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/piotr_bruunOP1 point·11 months ago

I am going to push back on this slightly.

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u/emil_wojcik1 point·11 months ago

never post a calculation as advice without stating the concentration

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u/piotr_bruunOP1 point·11 months ago

Cored the stopper on my 4th draw because I kept using the same entry point. Rotate the puncture site.

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u/arne_restrepo1 point·11 months ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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u/vial_math_veraMOD1 point·11 months ago·edited

Tracking number removed. It identifies both ends of a shipment.

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u/reflux_report1 point·11 months ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/piotr_bruunOP1 point·11 months ago

Cored the stopper on my 4th draw because I kept using the same entry point. Rotate the puncture site.

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u/anya_antonsen1 point·11 months ago

swirl, do not shake, or you are courting oxidation

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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