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c/orforglipron·submitted 8 days ago by u/deleted_my_history

[Speculation] what happens to the research-peptide supply chain if this lands

Speculationbranch of 7 comments

I have had 16 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 8 days on nominally the same lane, which matters more in summer than in February. The independent number came back 99.0% against a claimed…

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7 comments, started 7 days ago
u/camila_vasquez41 points·7 days ago·edited

Maintenance for 22 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/quiet_moderatormod33 points·7 days ago

the muscle cramps profile is speculative at this stage

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u/pancreatitis_scare16 points·6 days ago·edited

no cold chain means ATTAIN, if approved

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u/kenji_laurent4 points·6 days ago

Strongly agree. The supply impact would be huge.

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u/bastian_ekstrom1 point·5 days ago

the ACHIEVE is whether this actually works long-term

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u/cloudy_vial_carol3 points·6 days ago

small molecule purity is different testing than peptides

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u/sofia_petrescu34 points·7 days ago

Came off after 11 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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