my ApoB moved and I cannot work out whether method development is why
gradient. That is the whole post, but I will justify it. Everything else people worry about in c/dosinglogs is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort gradient out first, and almost nobody does. I say this having got it wrong for 23 months. My…
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
Dead space in the needle hub holds a small but non-trivial volume.
Adding to this: LC-MS is doing more work than the comment implies.
related substances are where the story lives, not the main peak
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
two labs, two different baselines, two different purity numbers, both honest
the detector wavelength matters more than people think
the gradient is doing the separation work, not the column alone
Slight fix: the number was 97.6, not 97.4. Decimal point, but a fairly consequential one.
Not convinced. The evidence does not support that reading.
a round-robin on baseline integration would be genuinely useful