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c/coldchain·posted 2 years ago by u/salma_vasquez

[Lab] SSA tirz — Medutest came back 97.4% against a claimed 96.2%

Question The Quiet One ×7 Slow Clap ×3 Receipts ×2

Week 55 update. 46kg down from the start, early fullness basically gone since about week 95.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

3,188 up / 167 down95% upvoted59 commentsid uab5az19 Oct 2023

59 comments

30 in this archive, depth 4

best — the order this archive was captured in

u/ewan_tulloch-28 points·2 years ago

Yeah, data logger is the only acceptable proof.

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u/transit_variance1 point·2 years ago·edited

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/chidi_abubakar1 point·2 years ago

the logger trace is the data that matters, not the packaging promises

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u/isabela_nilsen1 point·2 years ago

Reconstituted or dry powder?

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u/tidy_vialdrawer_watch281 point·2 years ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/niels_norgaard-41 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

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u/transit_variance1 point·2 years ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/meera_sandvik0 points·2 years ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/maren_sorensen1 point·2 years ago

You have restated the marketing copy. What is the actual substance here.

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u/spain_receta284 points·2 years ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/gustav_vermeulen412 points·2 years ago

no tracking numbers, no full addresses, no label photos — instant removal

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/salma_vasquezOP217 points·2 years ago

The gel pack lasted 10 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.

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u/salma_vasquezOP124 points·2 years ago

The gel pack lasted 5 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.

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u/search_before_post91 points·2 years ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/salma_vasquezOP414 points·2 years ago

Spain to Spain: 21 days with QSC and 23 days with GL Biochem. Same route, different carriers, variance is real.

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u/bastian_ekstrom136 points·2 years ago·edited

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/honest_syringe33209 points·2 years ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/amara_dziedzic137 points·2 years ago·edited

Strongly agree. Peak temperature is not the whole story.

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u/phase_two_pete65 points·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/nils_ferreira15 points·2 years ago

Strongly agree. Peak temperature is not the whole story.

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u/kian_solberg5 points·2 years ago

Slight fix: the number was 97.2, not 97.4. Decimal point, but a fairly consequential one.

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u/jarno_karlsen63 points·2 years ago

customs clearance often breaks the cold chain, factor that in

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u/emil_marchand52 points·2 years ago

customs clearance often breaks the cold chain, factor that in

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/usb_logger_ursulaMOD35 points·2 years ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/priya_weiss26 points·2 years ago

customs clearance often breaks the cold chain, factor that in

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u/reship_roulette17 points·2 years ago

Strongly agree. Peak temperature is not the whole story.

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[deleted]24 points·2 years ago

[deleted]

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u/maren_sorensen35 points·2 years ago·edited
source?
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u/phase_two_pete29 points·2 years ago

time-at-temperature integral is the dose, not just peak temperature

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u/solene_abubakar16 points·2 years ago

time-at-temperature integral is the dose, not just peak temperature

Disagree on that part. 95.1% and 96.2% on the same vial is normal.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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Independent HPLC and mass spec. The number you get is the number they found.

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c/coldchain rules
  1. Excursion claims need a logger trace or a photo taken at unboxing. "It felt warm" is not data.
  2. No tracking numbers, ever. They identify you and the recipient.
  3. Stability claims need a source or an explicit "this is my guess" label.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
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