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c/coldchain·posted 1 year ago by u/solene_abubakar

three years of excursion threads, summarised so you do not have to read them

Question Cold Box ×1 Well Actually ×2 Receipts ×3

Right, the stability question again, but with numbers this time.

I have 3 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 9, not week 58. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

12,590 up / 9,259 down58% upvoted50 commentsid s11rk115 Aug 2024

50 comments

20 in this archive, depth 4

best — the order this archive was captured in

u/usb_logger_ursulaMOD561 points·1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/isabela_nilsen137 points·1 year ago

Peak temperature and how long at that temperature?

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u/emeka_beaulieu343 points·1 year ago·edited
this is the third time this week and i love it every time
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u/isabela_nilsen290 points·1 year ago

a warm courier van is a bigger problem for a mixed vial than for dry powder

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u/milos_vestergaard213 points·1 year ago

Which carrier and route?

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u/soren_yildiz67 points·1 year ago·edited

data logger is the standard, gut feeling is not

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u/milan_mensah177 points·1 year ago

time-at-temperature integral is the dose, not just peak temperature

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[deleted]73 points·1 year ago

[deleted]

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u/solene_abubakarOP27 points·1 year ago

Customs clearance took 16 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.

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u/nikhil_asante155 points·1 year ago

Yeah, data logger is the only acceptable proof.

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u/solene_abubakar97 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/vito_chowdhury48 points·1 year ago

Not convinced. The evidence does not support that reading.

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u/sten_palacios-33 points·1 year ago

Canada to Canada takes 13 days on average, variance is 30 days

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u/anya_rautio92 points·1 year ago

Strongly agree. Peak temperature is not the whole story.

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u/solene_abubakarOP68 points·1 year ago

France to France: 6 days with BCH and 31 days with HJ. Same route, different carriers, variance is real.

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u/isabela_nilsen72 points·1 year ago·edited

gel packs last 2 hours, after that you are relying on the box itself

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u/usb_logger_ursula51 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/jarno_adeyemi17 points·1 year ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/mod_cold_roommod · c/coldchain0 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/emeka_beaulieu31 points·1 year ago·edited

This is correct. Dry powder is way more robust than liquid.

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Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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