someone explain cold chain to me like I have not read a paper in years
Trying to settle this properly because the thread from last year went in circles.
The claim: data logger matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 21 months without either producing anything.
What would actually settle it is 7 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
The gel pack lasted 2 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.
the logger trace is the data that matters, not the packaging promises
Flair changed to match the content. Read the sidebar before posting next time and we are square.
a warm courier van is a bigger problem for a mixed vial than for dry powder
Customs clearance took 7 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.
customs clearance often breaks the cold chain, factor that in
Sceptical. If this were true we would see it reflected in the data and we do not.
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
time-at-temperature integral is the dose, not just peak temperature
Disagree. What you are describing is consistent with data logger, not with what you concluded.
Logger trace from my shipment: 10 hours at 31°C. Powder tested 99.1% against 94.2% claim. Tolerates more than the box implies.
- 1The gel pack lasted 2 hours in a courier van, then liquid. Powder itself…6 comments in this branch · started by u/niels_norgaard