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c/bloodwork·posted 5 months ago by u/chidi_abubakar

[Question] New Zealand — has anyone got a straight answer on lipids

Question Long Haul ×6

eGFR. That is the whole post, but I will justify it.

Everything else people worry about in c/orforglipron is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort eGFR out first, and almost nobody does.

I say this having got it wrong for 4 months. My A1c was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

568 up / 194 down75% upvoted18 commentsid ygzq825 Feb 2026

18 comments

12 in this archive, depth 3

best — the order this archive was captured in

u/customs_seizure_sid84 points·5 months ago

ALT is where the fatty-liver story shows up first

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u/gentle_correctionnice about it29 points·5 months ago

Not convinced. The evidence does not support that reading.

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u/neha_rahimi49 points·5 months ago

the 5 month eGFR check is the routine

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u/jarno_karlsen36 points·5 months ago

Yeah, baseline matters more than any later number.

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u/liver_enzyme_lizMOD31 points·5 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/tidy_vialdrawer_watch-10 points·5 months ago

the 4 month bloodwork check is the routine

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u/yara_mensah20 points·5 months ago

HOMA-IR is crude but free and useful for tracking

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u/tidy_vialdrawer_watch9 points·5 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/chidi_abubakarOP6 points·5 months ago

My ALT went from 18 to 16 in 42 weeks. The ApoB story shows up in the trend, not the single number.

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u/milos_trevino4 points·5 months ago

Do you have baseline to compare to?

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u/gustav_cardoso8 points·5 months ago

This is correct. ApoB is the better marker.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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