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c/bloodwork·posted 1 year ago by u/cardio_endpoint_c

[Results] 61 weeks on 12.5mg, full numbers, ask me anything boring

Results Receipts ×8 Well Actually ×3 Slow Clap ×1

Something I noticed reading old threads that I have not seen said out loud.

The advice on lipids in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

4,958 up / 765 down87% upvoted42 commentsid 35vu6d18 May 2025

42 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/kenji_kimani486 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/a1c_arcMOD256 points·1 year ago·edited

Removed a chain here. The rule is one line long and it is not negotiable.

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[removed]110 points·1 year ago

[removed by moderator]

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u/cormac_roos-1 point·1 year ago

Removed a chain here.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/nabila_bakken295 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/thermal_mass_tom107 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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u/noor_hovland73 points·1 year ago

eGFR noise during rapid loss is expected

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u/gustav_cardoso245 points·1 year ago

I am going to push back on this slightly.

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u/mikkel_ogunleye185 points·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/lipid_panel_larrybloodwork111 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/cormac_roos83 points·1 year ago

Disagree. What you are describing is consistent with eGFR, not with what you concluded.

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u/neha_rahimi44 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/elin_varga29 points·1 year ago

baseline is the most important eGFR measurement, you cannot collect it later

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u/elin_trevino172 points·1 year ago

Do you have baseline to compare to?

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u/cardio_endpoint_cOP135 points·1 year ago

ALT is where the fatty-liver story shows up first

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u/edit_for_clarity58 points·1 year ago·edited

What are your reference ranges?

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u/janek_ferrari68 points·1 year ago

Do you have baseline to compare to?

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u/skip_week_sceptic81 points·1 year ago

nobody here can tell you what a result means for you

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u/gustav_cardoso97 points·1 year ago

TSH from 15 to 35 is movement, not noise

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u/tomas_kimani107 points·1 year ago

the 23 month bloodwork check is the routine

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u/customs_seizure_sid59 points·1 year ago

ALT is where the fatty-liver story shows up first

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u/thermal_mass_tom55 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/karl_fischer_kev19 points·1 year ago

Not to be pedantic but A1c and lipids are being used interchangeably and they are not interchangeable in real life.

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u/greta_chukwu13 points·1 year ago

Yeah, baseline matters more than any later number.

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u/noor_cardoso65 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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u/hedda_adeyemi17 points·1 year ago

eGFR noise during rapid loss is expected

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u/cardio_endpoint_cOP6 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/bence_zamora75 points·1 year ago

Yeah, baseline matters more than any later number.

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u/cardio_endpoint_cOP59 points·1 year ago

Baseline ferritin: 98.3. Week 89: 97.9. Same lab, fasted, same time of day. Trend matters.

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u/step_therapy_s16 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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