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c/bloodwork·posted 4 months ago by u/customs_seizure_sid

ApoB: the version I wish someone had shown me in week 1

Concerning

Something I noticed reading old threads that I have not seen said out loud.

The advice on lipids in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

393 up / 146 down73% upvoted22 commentsid 2we7l121 Mar 2026

22 comments

16 in this archive, depth 3

best — the order this archive was captured in

u/coa_forgery_watch26 points·4 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/heart_rate_bump-25 points·4 months ago

I am going to push back on this slightly.

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u/lipid_panel_larrybloodwork1 point·4 months ago

baseline is the most important A1c measurement, you cannot collect it later

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u/leila_vasquez15 points·4 months ago·edited

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/yara_mensah11 points·4 months ago

Strongly agree. ALT is where you catch the liver story early.

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u/noor_cardoso7 points·4 months ago

eGFR noise during rapid loss is expected

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[deleted]3 points·4 months ago

[deleted]

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u/karl_fischer_kev9 points·4 months ago

Strongly agree. ALT is where you catch the liver story early.

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u/liver_enzyme_lizMOD7 points·4 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/nikhil_asante4 points·4 months ago·edited

You have restated the marketing copy. What is the actual substance here.

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u/burned_once_twice2 points·4 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/pavel_nkemelu2 points·4 months ago

What are your reference ranges?

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u/freya_baptista2 points·4 months ago·edited

A1c moves slowly, quarterly is plenty

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u/emil_okwuosa1 point·4 months ago

Respectfully this is a sample of one presented as a finding.

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u/valeria_karlsen1 point·4 months ago

Disagree. What you are describing is consistent with ferritin, not with what you concluded.

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u/pavel_nkemelu1 point·4 months ago

Disagree.

Yes, exactly this, and it is the bit that took me 4 weeks to accept.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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