u/rasmus_kimani

This is correct. Process matters more than the number.

I am going to push back on this slightly.

do not extrapolate rodent data to human dosing without saying so

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

Are you on a pen or research vial? Because the trajectory is different.

week 47 on the pen, 20kg down, this is the answer

post the spreadsheet

Yes, exactly this, and it is the bit that took me 58 weeks to accept.

A shoulder on the main peak that 19 analysts integrated 26 different ways. Same trace, 99.2 spread.

chromatogram or it did not happen

The PeptideMeter result being close to my own HPLC is the signal, not the absolute number. Both are right.

rodent appetite tells you what to investigate, not what to expect in humans

Respectfully this is a sample of one presented as a finding.

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

Second this question. I have wondered about T2D for 10 months and never seen a straight answer.

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

metformin combo is standard

Maintenance for 12 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

Sceptical. If this were true we would see it reflected in the data and we do not.

Maintenance for 14 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

cite the paper: journal, year, first author, links optional